Producing human tissue plasminogen activator (t-PA) in Chinese hamster ovary (CHO) cells is an example of genetic engineering, as it involves the introduction and manipulation of specific genes in the CHO cells to enable them to produce the desired protein, t-PA.
Genetic engineering refers to the process of modifying the genetic material of an organism to introduce new traits or characteristics. In the case of producing t-PA in CHO cells, genetic engineering techniques are used to insert the gene responsible for producing t-PA into the CHO cell's genome.
The process involves several steps. First, the gene encoding t-PA is isolated from human cells or synthesized in the laboratory. The gene is then inserted into a vector, such as a plasmid, which acts as a carrier to deliver the gene into the CHO cells. The vector containing the t-PA gene is introduced into the CHO cells through a process called transfection.
Once inside the CHO cells, the t-PA gene integrates into the cell's genome. The cells are then cultured under controlled conditions that promote gene expression and protein production. The CHO cells utilize their cellular machinery to transcribe and translate the t-PA gene, resulting in the synthesis of t-PA protein.
The genetically engineered CHO cells can be grown in large quantities and harvested to extract the produced t-PA. The t-PA protein can then be purified and used as a therapeutic agent for medical applications, such as treating blood clotting disorders.
Overall, the production of t-PA in CHO cells through genetic engineering demonstrates how the manipulation of genes in cells can lead to the production of specific proteins with therapeutic or industrial value.
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A molecule has been isolated from a cell. The molecule is found to be in a ring shape made up of carbon, hydrogen, and oxygen atoms in a 1:2:1 ratio. Choose all the statements that apply to this molecule.
Based on the information given, the following statements likely apply to the molecule:
- The molecule is an organic compound, as it contains the elements carbon, hydrogen, and oxygen.
- The molecule is likely a carbohydrate, as many carbohydrates have a ring shape and a 1:2:1 ratio of carbon, hydrogen, and oxygen atoms.
- The molecule is likely a sugar, as many sugars are ring-shaped carbohydrates
- The molecule is likely a monosaccharide. Monosaccharides are simple sugars and are the building blocks of more complex carbohydrates like disaccharides and polysaccharides. They are composed of C, H, and O in a ratio of 1:2:1, fitting the information provided.
- The molecule is likely to be a cyclic compound, due to the ring shape made up of atoms.
It is important to note that this information is not enough to definitely identify the molecule, there are several compounds that can fit in this description such as Glucose, Fructose, and Ribose. Additional information and testing would be needed to definitively identify the molecule.
the folded organelle just outside of the nucleus that is covered in ribosomes and plays a role in protein synthesis is called the:
Answer:
endoplasmic reticulum (ER)
Explanation:
which phrase best describes the function of the atp molecule?
Answer:
Carries energy is a phrase that best describes the function of the ATP molecule.
what is a bomite mineral?
Answer: bornite
Explanation: A copper-ore mineral, copper and iron sulfide (Cu5FeS4). Typical occurrences are found in Mount Lyell, Tasmania; Chile; Peru; and Butte, Mont., U.S. Bornite, one of the common copper minerals, forms isometric crystals but is seldom found in these form
Do you agree with this quote? Explain your reasoning using your understanding of the genetics of skin color.
Answer: No
Explanation:
There is no quote to see therefore I cannot agree.
Gregor thinks that anthills are wider when the ground is muddy. he created the table below. is his investigation a scientific experiment
In the case above, His investigation is scientific but it is not an experiment because he does not manipulate variables.
What is the investigation?In controlled research, an experiment usually includes the manipulation of variables to respect the happening belongings. However, not all controlled studies need to be experiments.
In Gregor's case, if he is not maneuvering variables but alternatively making remarks and illustration ends based on those notes, welcome review can still be thought-out scientific, but not an experiment.
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See text below
Gregor thinks that anthills are wider when the ground is muddy. He creates the following table. Is Gregor’s investigation a scientific experiment?
His investigation is scientific but it is not an experiment because he does not manipulate variables.
His investigation is a scientific experiment because he is taking measurements to confirm a hypothesis.
His investigation is not scientific but it is an experiment because he is comparing evidence of multiple observations.
His investigation is not scientific and it is not an experiment because he is just making observations.
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Which of these converts the biomass of a dead organism into simple soluble
substances in the soil?
A: Detritus feeders
B: Large animals
C: Decomposers
D: All of these
1 2 3
4
7
8
Which phase of an ambulance call is characterized by receiving a report from the off going shift and checking the functionality equipment?
Preparing for the ambulance call phase of an ambulance call is characterized by receiving a report from the off going shift and checking the functionality equipment.
For one, Ambulance is effortlessly Bay's best film in ages – arguably on the grounds that his lizard-brained masterwork awful Boys II, and perhaps even for the reason that Rock. The movie, whilst some distance from a lean, most economical affair, is also agreeably scaled lower back for this famously maximalist director.
She informs her with a view to store each of her and Zach's lives during their getaway. Zach defends Will as well. While he's still bound to his hospital mattress, Zach identifies Will's heroism to the officials who question him. Zach additionally gets a reunion along with his partner, Mark (Cedric Sanders).
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a. the capillaries supplying blood to the area become more leaky (i.e., permeable). b. prostaglandins deaden nerve endings, alleviating pain. c. neutrophils release histamine. d. the capillaries supplying blood to the area constrict (become smaller). e. all of the above
None of the options a, b, c, or d fully explains the process of inflammation. However, option "e" is the correct answer as all of the listed options are part of the process of inflammation.
During inflammation, several changes occur in the affected area, including increased capillary permeability, which allows immune cells and fluid to enter the area, and the release of chemical mediators such as prostaglandins and histamine. Prostaglandins can both promote and reduce inflammation, depending on the specific circumstances, while histamine can cause vasodilation (widening of blood vessels), leading to increased blood flow to the area.
These changes are intended to help the body fight infection or repair damaged tissue, but they can also cause pain, swelling, and redness in the affected area. Therefore, inflammation is a complex and multi-faceted process that involves a variety of cellular and molecular mechanisms.
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How do homologous features display evidence of divergent evolution
answer
Homologous structures are present in many different species that share a common ancestor. the structure are anatomically similar and persist in the different species.
This is evident of divergent evolution because it shows that different animals come from a common ancestor but evolve o become different species from each other.
How are alleles represented in genetics?
Biologists refer to dominant alleles as uppercase letters and recessive alleles as lowercase letters when referring to genotype.
What are alleles?Genetics and evolution define an allele as a variant of the same sequence of nucleotides at the same location on a lengthy DNA molecule.
The variant DNA sequences at a locus are known as alleles, and the chromosomal or genomic location of a gene or any other genetic element is referred to as a locus.
Alleles can be identified using just one capital or lowercase letter, two, three, or more letters, or letter/number combinations. Superscripts, subscripts, or both may be present in alleles.
Alleles that are recessive are denoted by lowercase letters, while dominant alleles are denoted by capital letters.
Thus, this way, the alleles are represented.
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Bio_U02_NGSQ1_FY21
Questi
What is the difference between eukaryotic and prokaryotic cells?
o Eukaryotic cells are found in bacteria and prokaryotic cells are not.
O Prokaryotic cells are found in plants and animals and eukaryotic cells are not
Eukaryotic cells contain organelles and DNA enclosed within a nucleus and prokaryotic cells do not.
Prokaryotic cells contain no organelles except DNA enclosed within a nucleus and eukaryotic cells do not
Answer:
Eukaryotic cells contain organelles and DNA enclosed within a nucleus and prokaryotic cells do not.
Explanation:
eukaryotic cells have a nuclius, prokaryotic cells don't.
Sarah believes that only animals undergo cellular respiration. Drew believes that both plants and animals undergo cellular respiration. Only one student is correct. Which answer choice BEST explains why?
not all the data in a dns cache has an expiration value.true or false?
The statement is True, not all the data in a DNS cache has an expiration value. DNS (Domain Name System) cache is a temporary database maintained by a DNS resolver on a user's computer. It stores DNS query results for a specific period to speed up future requests for the same domain name.
DNS servers contain a list of domain names that they have recently resolved, allowing them to respond quickly to new requests for the same domain name.Certain types of DNS records, such as A records, typically have an expiration value known as a TTL (Time-to-Live). This value determines the length of time a DNS resolver is allowed to cache the results of a DNS query.
However, not all types of DNS records have an expiration value, such as NS records, which specify the authoritative DNS servers for a domain name. These records are not subject to expiration, and the DNS resolver must make a new query to retrieve the updated information. Therefore, while TTLs are commonly used to control caching behavior, not all data in a DNS cache has an expiration value.
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Sister chromatids move to the poles of dividing cells during _______________; their movement is facilitated by ________________which connect spindle fibers to the chromatids. a. prophase; actin fibers b. anaphase; myosin motors c. anaphase; kinetochores d. metaphase; securing
Sister chromatids move to the poles of dividing cells during anaphase. Their movement is facilitated by kinetochores which connect spindle fibers to the chromatids.
Sister chromatids are two identical copies of a single chromosome joined at the centromere in preparation for cell division. Following replication in the S phase of interphase, sister chromatids remain attached to each other until their separation in the anaphase stage of mitosis or meiosis II. Anaphase is the fourth stage of mitosis where sister chromatids separate and move to opposite poles of the cell.
During this phase, the spindle fibers attached to kinetochores pull the sister chromatids toward the poles of the cell.As we can see that, the given terms of the question- Sister chromatids move to the poles of dividing cells during anaphase; their movement is facilitated by kinetochores which connect spindle fibers to the chromatids. Hence, the correct answer is option C) Anaphase; Kinetochores.
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Is the Once-ler greedy? Why do you think so?
The Lorax and its 2012 film version both have The Once-ler as their narrator. He is a rapacious industrialist who destroyed the entire Truffula Tree in order to produce a strange garment called a Thneed, or "a Fine Thing That All People Need."
The Once-ler one day finds a valley full of stunning Truffula trees that are home to Bar-ba-Loots, Swommee Swans, and Humming Fish. To make room for his creation, the Thneed, he chooses to chop down one of the trees. He discovers The Lorax in the tree trunk after felling a Truffula Tree. He is warned not to clear the forest for his selfish purposes. The Once-ler refuses to take advice and keeps felling trees to make things to sell.
He was unable to accept what he had done:
It's simple for us to see the Once-ler as a ruthless antagonist. He wrecked a once-beautiful and prosperous region because he was only thinking about himself. Even money didn't appear to be driving the Once-ler. He never lived in a luxurious environment and instead only consumed for the sake of unrestrained growth.
Danny DeVito Advocates for Trees and Discusses "Dr. Seuss" The Lorax:
He wasn't able to see the effects of his acts until it was too late. Once-ler was broken by the truth. He wreaked so much damage that his identity eventually crumbled. He withdrew to his house and disappeared from public view.
It's a tale of wasted talent:
The Once-ler was a true genius, despite the fact that he sometimes utilized his talents for bad. His curiosity and creativity were beyond bounds. There was no issue that he couldn't come up with a solution for. His inventions had a profound impact on society. He made significant innovations. The Lorax is a tale about lost talent as well as one that serves as a warning against greed. By the story's conclusion, nobody has any recollection of the Once-accomplishments ler's or even his identity. All of his genius was gone due to his horrible legacy. Ultimately, his extraordinary mind is simply one of the many resources that his avarice wasted.
He Was Abandoned and Used:
The Once-ler gave in to the pressures his avaricious relatives imposed on him. They lost all sense of perspective when they realized the money that could be made from the needs. His domineering mother was maybe the greediest of them all. Profits dried up as the planet became ever more poisonous and truffula fluffs decreased. When your source material has been harvested dry, it is difficult to keep up with the surge in demand. The money also ran out when the fluffs did. When the money stopped coming in, the Once-ler was left alone. also his mother. Nobody deserves to be abandoned, especially not because of money.
He is engulfed with shame:
The Once-ler is almost pathologically brash for the most of the narrative. He intends to seize anything he can, even if it means destroying it. He appears to be binge-consuming. He seems to just mindlessly eat everything in his path without even making any plans for his requirements in the future. before it is too late. The shame of his actions won't completely hit home for him until the forest is devastated and the final truffula tree falls. The Once-ler begins to live alone. He covers his face from everyone because he is ashamed of what he has done to the once-beautiful forest.
He Is Conscientious:
The Once-ler makes a surprise decision towards the end of the narrative. He then hands the final truffula tree seed to his small audience as he finishes the story. For the majority of the novel, we don't really get to know him, but now we do. He feels bad since he is aware of how awful what he did is. After causing the forest such severe harm, he wants to see it recover. Throughout the entire narrative, he is portrayed as the antagonist, a callous and self-centered individual. With this one kind deed, can he really atone for himself?
He’s Terrified Of Failure:
The final truffula seed, the secret weapon the Once-ler has been holding all along, is revealed as the story draws to a close. The story's most perplexing section is this. He has been hiding from the outside world by sitting in his home. He had yearned to see woods and animals once more for years, consumed with anguish and shame. He had the solution to his own problem in his hands the entire time. Why didn't he just put the seed in the ground himself? Considering his fear that everything he touches would result in death and ruin. He simply doesn't have faith in himself to accomplish it correctly.
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which is a requirement for the existence of a metapopulation?i. a system of habitat corridors that link individual populationsii. the presence of both r- and k-selected speciesiii. variation in the size of individual populations
These separated populations are linked by strips of natural niche that are known as corridors. The demand for the actuality of a metapopulation is a system of niche corridors that link individual populations.
Astronomically speaking, a metapopulation is a group of populations( frequently called * subpopulations) that enthral spatially distinct niche patches that are close enough to support disbandment among patches. We frequently suppose similar models as “ spatially structured ” or “ spatially unequivocal ”, although some metapopulation models( like the models considered below, and in the Gotelli text) use a rather abstract representation of space!
Now that we ’re allowing creatures living in particular areas in space, we need to incorporate information about movement ecology in addition to population ecology! Patches in a metapopulation are connected viadispersal. However, it wouldn’t really be a metapopulation, but rather a set of insulated populations that you could model singly, If there were no connectivity( disbandment among patches).
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_______ goods are usually located close to the checkout counter because consumers will put forth a minimum level of effort to obtain them. Convenience Unsought Shopping Specialty
Convenience goods are usually located close to the checkout counter because consumers will put forth a minimum level of effort to obtain them.
Convenience goods are products that are frequently purchased by consumers due to their routine or everyday use. These goods are typically low-priced, widely available, and require minimal effort to purchase. Placing them near the checkout counter is a strategic placement strategy as it allows for impulse purchases and provides convenience to customers who may want to grab a last-minute item before completing their transaction.
By underlining and bolding the answer, it is clear that convenience goods are the ones commonly found near the checkout counter for easy access and minimal effort from consumers.
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What progress has been made in the HIV epidemic?
It is now possible to take a combination of HIV-fighting drugs, also called antiretroviral therapy, that prevents AIDS from developing when the virus is in the body.
if you mean where it leads to I say HIV leads to AIDS or in other words...progress has been made towards the goal of ending the HIV/AIDS epidemic due to advancements in both prevention and treatment.
hope this helps!
Blood platelets help in
(a) formation of urine
(b) excretion of urine
(c) sweating
(d) blood clotting
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Blood platelets help in blood clotting.
Option d is the correct answerPlatelets are tiny blood cells that help your body form clots to stop bleeding.
the amount of air that remains in the lungs simply to keep them open is called the:
The amount of air that remains in the lungs to keep them open is called the functional residual capacity (FRC).
It is a vital measure of lung function and plays a crucial role in maintaining proper respiratory mechanics.
The functional residual capacity (FRC) represents the volume of air that remains in the lungs at the end of a normal tidal breath, when the individual is at rest and not actively breathing in or out.
It is the equilibrium point between the elastic recoil of the lungs (which tends to collapse the lungs) and the elastic recoil of the chest wall (which tends to expand the lungs). The FRC consists of two components: the expiratory reserve volume (ERV), which is the volume of air that can be exhaled after a normal exhalation, and the residual volume (RV), which is the volume of air that remains in the lungs after a maximal exhalation. The FRC is essential for maintaining the patency of the airways and preventing lung collapse, ensuring that the lungs are ready for the next breath.
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Can someone explain how it is possible for a single molecule of steroid hormone to create a significant and lasting response in an organisms cell?
Answer:
half life and higher affinity
Explanation:
it is because they have long half life in blood and high affinity
Steroid hormone
The cell signaling pathways induced by the steroid hormones regulate specific genes within the cell's DNA. The hormones and receptor complex act as transcription regulators by increasing or decreasing the synthesis of mRNA molecules from specific genes.Steroid hormones are not able to target every cell within the body, so the overall response is slower. They bind to receptors on the cell's surface and the receptors aid in helping the steroid hormones enter the cell.Hormones work by binding to protein receptors either inside target cells or on their plasma membranes. The binding of a steroid hormone forms a hormone-receptor complex that affects gene expression in the nucleus of the target cell.Steroids pass into a cell's nucleus, bind to specific receptors and genes and trigger the cell to make proteins.Learn more:
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Why are indicated gene expression in stem cells versus specialized ( differentiated) cells
Gene expression in stem cells is more versatile and pluripotent, allowing them to differentiate into various cell types, while specialized cells have specific gene expression patterns that enable them to perform their specialized functions
Gene expression in stem cells and specialized (differentiated) cells differs due to their distinct roles and functions in the body. Stem cells have the unique ability to differentiate into various cell types, whereas specialized cells have already undergone differentiation and acquired specific functions.
In stem cells, gene expression is more pluripotent, meaning a wide range of genes can be activated or repressed to maintain their self-renewal and differentiation potential. This flexibility allows stem cells to respond to different signals and stimuli, enabling them to give rise to different cell lineages during development or tissue regeneration.
On the other hand, specialized cells have undergone a process called cell differentiation, where specific genes are selectively expressed or silenced to establish their specialized functions and morphology. Gene expression in specialized cells is more restricted and specific, as it is essential for the cell to perform its designated role effectively and maintain tissue homeostasis.
The regulation of gene expression in stem cells and specialized cells involves complex molecular mechanisms, including the activation or repression of transcription factors, epigenetic modifications, and signaling pathways. These mechanisms ensure the appropriate gene expression patterns in different cell types, allowing for proper development, tissue function, and overall organismal health.
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The subject above ingests 3 liters of water. Assuming no water loss from the body, the plasma osmolarity in mOsm/liter after steady state has been attained will be: a. 260 0. 265 270 d. 275 e. 280
Assuming no water loss from the body, the plasma osmolarity in mOsm/liter after steady state has been attained will be 265.
This is because the normal plasma osmolality is approximately 280 mOsm/L, and the ingestion of 3 liters of water will dilute the plasma by lowering its osmolality to about 265 mOsm/L.
The plasma osmolality is a measure of the concentration of dissolved particles, such as sodium, potassium, and urea, in the blood. Normally, the plasma osmolality is maintained within a narrow range of 280-295 mOsm/L, which is essential for proper cellular function.
When an individual ingests a large volume of water, the plasma volume increases, and the plasma osmolality decreases. This is because water is a hypotonic solution, meaning that it has a lower concentration of dissolved particles than the plasma.
Assuming no water loss from the body, the plasma osmolarity in mOsm/liter after steady state has been attained will be 265. This is because the ingestion of 3 liters of water will dilute the plasma by lowering its osmolality to about 265 mOsm/L. However, this assumes that there is no loss of water from the body, which is unlikely to be the case in reality.
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CAN SOMEONE HELP PLEASE
Which section of ocean floor is near the coastlines of all continents?
A. neritic zone
B. open ocean
C. shallow ocean
D. intertidal zone
NO, it is NOT D. intertidal zone like all the other Brainly answers to the question says.
THE CORRECT ANSWER IS C. SHALLOW OCEAN on edg 2022
Answer:
c
Explanation:
Answer:
c. shallow ocean
Explanation:
correct on edg 2022
48. In the urea cycle, the SECOND nitrogen of urea originates form which of the following metabolites? a. alanine c. glutamine b. aspartate d. arginine 49. A person with phenylketonuria cannot convert
Option A: In the urea cycle, the second nitrogen of urea originates from alanine.
Option A: Phenylketonuria prevents the conversion of phenylalanine to tyrosine.
The aspartate and glutamate breakdown of amino acids provides the first nitrogen for urea in the urea cycle. The second nitrogen in urea, though, comes from alanine. A source of the second nitrogen atom required for the formation of urea, alanine is an amino acid that can be transformed to pyruvate and subsequently enter the urea cycle.
Phenylalanine is a crucial amino acid which needs to be converted into tyrosine. This conversion is brought in by an enzyme called phenylalanine hydroxylase. Lack of this enzyme results in the genetic disorder known as phenylketonuria (PKU). Tyrosine deficiency and phenylalanine accumulation are symptoms of PKU. This imbalance can have detrimental effects on brain development and function if not properly managed through dietary restrictions.
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Complete question:
48. In the urea cycle, the SECOND nitrogen of urea originates form which of the following metabolites? a. alanine c. glutamine b. aspartate d. arginine
49. A person with phenylketonuria cannot convert
A. phenylalanine to tyrosine
B. phenylalanine to isoleucine
C. phenol into ketones
D. phenylalanine to lysine
Which of the following statements about the skeletal system is false
Answer:
C is False..
Hope this helps..
Explanation:
The human skeleton is the internal framework of the human body. It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. The bone mass in the skeleton reaches maximum density around age 21.
Where are sugar and oxygen removed from the blood?
Hint: Sugar and oxygen are processed here to
release usable energy
Please explain this.
Sugar and oxygen are removed from the blood primarily in the cells of body tissues during cellular respiration.
During cellular respiration, sugar (glucose) and oxygen are combined in the presence of enzymes within the cells to produce usable energy in the form of adenosine triphosphate (ATP). This process occurs in the mitochondria, which are organelles found in most cells. The mitochondria are often referred to as the "powerhouses" of the cells because they generate ATP through the breakdown of glucose and the utilization of oxygen.
Within the mitochondria, a series of biochemical reactions take place, collectively known as the citric acid cycle and the electron transport chain. These processes break down the glucose molecule and transfer high-energy electrons to generate ATP. Oxygen acts as the final electron acceptor in the electron transport chain, enabling the efficient production of ATP.
As glucose is broken down and ATP is produced, carbon dioxide and water are generated as byproducts. Carbon dioxide is transported back into the blood and carried to the lungs, where it is exhaled. Oxygen is continuously supplied to the cells through the bloodstream, ensuring the availability of this crucial molecule for cellular respiration.
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Fossil skulls of Dimetrodon show that it had large, strong bones in its head for the attachment of its jaw muscles. Suggest how this adaptation could help it to survive?
Answer:
Dimetrodon (/daɪˈmiːtrədɒn/ (About this soundlisten) or /daɪˈmɛtrədɒn/, meaning "two measures of teeth") is an extinct genus of non-mammalian synapsid that lived during the Cisuralian (Early Permian), around 295–272 million years ago (Ma).It is a member of the family Sphenacodontidae. The most prominent feature of Dimetrodon is the large neural spine sail on its back formed by elongated spines extending from the vertebrae. It walked on four legs and had a tall, curved skull with large teeth of different sizes set along the jaws. Most fossils have been found in southwestern United States, the majority coming from a geological deposit called the Red Beds of Texas and Oklahoma. More recently, fossils have been found in Germany. Over a dozen species have been named since the genus was first erected in 1878.
Explanation: